import { defineComponent, computed, ref } from 'vue';
/*
class GrainInput {
static inputs = [];
name;
unit;
mpg;
inputEl;
reference;
* @param {{
* name: string,
* mpg: number,
* reference: GrainInput | 'self',
* unit: string,
* step?: number,
* }} opts
constructor(opts) {
this.name = opts.name;
this.mpg = opts.mpg;
this.unit = opts.unit;
this.reference = opts.reference === "self" ? this : opts.reference;
this.inputEl = h("input", { type: "number", min: 0, step: opts.step ?? 1 });
eventBus.addListener(this);
}
attachInput(insertionPoint) {
insertionPoint.appendChild(this.inputEl);
this.inputEl.valueAsNumber = this.mpg;
this.inputEl.addEventListener("input", (e) => {
const newVal = (e.currentTarget)?.valueAsNumber ?? 0;
if (this !== this.reference) {
this.reference.inputEl.valueAsNumber = newVal / this.mpg;
}
eventBus.sendChange(this);
});
}
onChange() {
if (!this.reference || this === this.reference) return;
this.inputEl.valueAsNumber = this.mpg * this.reference.inputEl.valueAsNumber;
}
getCurrentValue() {
return this.inputEl.valueAsNumber;
}
}
class RatiosController {
t3Ratio = h("input", { type: "number", min: 0, step: 1 });
t4Ratio = h("input", { type: "number", min: 0, step: 1 });
t3Syn = h("input", { type: "number", min: 0 });
t4Syn = h("input", { type: "number", min: 0 });
t3 = 1;
t4 = 4;
reference;
constructor(referenceInput) {
this.reference = referenceInput;
}
attachInputs(inputs) {
inputs.t3Ratio.replaceWith(this.t3Ratio);
inputs.t4Ratio.replaceWith(this.t4Ratio);
inputs.t3Syn.replaceWith(this.t3Syn);
inputs.t4Syn.replaceWith(this.t4Syn);
this.t3Ratio.addEventListener("input", (e) => {
const newVal = (e.currentTarget)?.valueAsNumber ?? 0;
this.t3 = newVal;
this.onChange();
});
this.t4Ratio.addEventListener("input", (e) => {
const newVal = (e.currentTarget)?.valueAsNumber ?? 0;
this.t4 = newVal;
this.onChange();
});
this.t3Syn.addEventListener("input", (e) => {
const newVal = (e.currentTarget)?.valueAsNumber ?? 0;
this.reference.inputEl.valueAsNumber = newVal / MPG_T3_SYN + this.t4Syn.valueAsNumber / MPG_T4_SYN;
this.t3 = newVal;
this.t4 = this.t4Syn.valueAsNumber;
this.updateRatio();
this.updateSyn();
eventBus.sendChange(this);
});
this.t4Syn.addEventListener("input", (e) => {
const newVal = (e.currentTarget)?.valueAsNumber ?? 0;
this.reference.inputEl.valueAsNumber = newVal / MPG_T4_SYN + this.t3Syn.valueAsNumber / MPG_T3_SYN;
this.t3 = this.t3Syn.valueAsNumber;
this.t4 = newVal;
this.updateRatio();
this.updateSyn();
eventBus.sendChange(this);
});
eventBus.addListener(this);
this.onChange();
}
onChange() {
this.updateRatio();
this.updateSyn();
}
updateRatio() {
this.t3Ratio.valueAsNumber = this.t3;
this.t4Ratio.valueAsNumber = this.t4;
}
updateSyn() {
const total = this.t3 + this.t4;
const t3Proportion = this.t3 / total;
const t4Proportion = this.t4 / total;
const grainsSyn = t3Proportion / MPG_T3_SYN + t4Proportion / MPG_T4_SYN;
const multiplierSyn = this.reference.getCurrentValue() / grainsSyn;
this.t3Syn.valueAsNumber = t3Proportion * multiplierSyn;
this.t4Syn.valueAsNumber = t4Proportion * multiplierSyn;
}
}
class ThyroidConverter extends DJElement {
static styles = css``;
static template = html;
constructor() {
super();
const mainGrainInput = new GrainInput({
name: "Grains",
mpg: 1,
reference: "self",
unit: "",
step: 0.1,
});
const ratiosController = new RatiosController(mainGrainInput);
const inputs = [
mainGrainInput,
new GrainInput({
name: "Armour, Natural Dessicated Thyroid",
mpg: 60,
unit: "mg",
reference: mainGrainInput,
}),
new GrainInput({
name: 'Liothyronine (Triiodothyronine, "Cytomel", T3)',
mpg: MPG_T3_SYN,
unit: "mcg",
reference: mainGrainInput,
}),
new GrainInput({
name: 'Levothyroxine (Thyroxine, "Cynoplus", T4)',
mpg: MPG_T4_SYN,
unit: "mcg",
reference: mainGrainInput,
}),
];
const tableBody = qs("#table-body", this.root);
const compoundedStart = qs("#compounded-start", this.root);
for (const field of inputs) {
const newRow = h("tr", {}, [
h("td", { textContent: field.name }),
h("td", {}, [
h("div", { className: "input", style: "display: inline-block;" }),
h("span", { className: "breathe", textContent: field.unit }),
]),
]);
field.attachInput(qs("div.input", newRow));
tableBody.insertBefore(newRow, compoundedStart);
}
ratiosController.attachInputs({
t3Ratio: qs(".ratios .t3", tableBody),
t4Ratio: qs(".ratios .t4", tableBody),
t3Syn: qs(".synthetic .t3", tableBody),
t4Syn: qs(".synthetic .t4", tableBody),
});
}
}
*/
export default defineComponent({
name: 'ge-calculator',
setup() {
const t3Ratio = ref(1);
const t4Ratio = ref(4);
const MPG_T3_SYN = 25;
const MPG_T4_SYN = 100;
const inputDefs = [
{
name: "Grains",
mpg: 1,
unit: "",
step: 0.1,
},
{
name: "Armour, Natural Dessicated Thyroid",
mpg: 60,
unit: "mg",
},
{
name: 'Liothyronine (Triiodothyronine, "Cytomel", T3)',
mpg: MPG_T3_SYN,
unit: "mcg",
},
{
name: 'Levothyroxine (Thyroxine, "Cynoplus", T4)',
mpg: MPG_T4_SYN,
unit: "mcg",
},
];
const numGrains = ref(2);
const ratio = computed(() => t3Ratio.value + t4Ratio.value);
const compounded = computed(() => {
const total = t3Ratio.value + t4Ratio.value;
const t3Proportion = t3Ratio.value / total;
const t4Proportion = t4Ratio.value / total;
const grainsSyn = t3Proportion / MPG_T3_SYN + t4Proportion / MPG_T4_SYN;
const multiplierSyn = numGrains.value / grainsSyn;
return {
t3Syn: t3Proportion * multiplierSyn,
t4Syn: t4Proportion * multiplierSyn,
};
});
return () => <>
Thyroid Calculator
Use this calculator to convert between different forms and units of thyroid hormone. Common synthetic, pure and natural dessicated forms are listed. The last section of the table provides input fields for a specified ratio of T3 to T4, and will give the dosages required for both the synthetic and pure forms. All dosages given are based on the "Grains" field at the beginning of the table, but editing any field will automatically update the rest to keep them in sync.
{ _.name } |
{
const val = (e.target as HTMLInputElement).valueAsNumber;
if (_.name === 'Grains') {
numGrains.value = val;
} else {
numGrains.value = _.mpg / val;
}
}}
min="0"
step={ _.step ?? 1 }
type="number" />
{ _.unit }
|
Compounded (T3 and T4, "Cynpolus") | |
Desired Ratio (T3:T4) |
{
t3Ratio.value = (e.currentTarget as HTMLInputElement).valueAsNumber;
}}
min="0"
step="1"
type="number" />
:
{
t4Ratio.value = (e.currentTarget as HTMLInputElement).valueAsNumber;
}}
min="0"
step="1"
type="number" />
|
Synthetic T3/T4 Combo |
{
t4Ratio.value = compounded.value.t4Syn;
t3Ratio.value = (e.currentTarget as HTMLInputElement).valueAsNumber;
numGrains.value = t3Ratio.value / MPG_T3_SYN + t4Ratio.value / MPG_T4_SYN;
}}
min="0"
step="1"
type="number" />
:
{
t3Ratio.value = compounded.value.t3Syn;
t4Ratio.value = (e.currentTarget as HTMLInputElement).valueAsNumber;
numGrains.value = t3Ratio.value / MPG_T3_SYN + t4Ratio.value / MPG_T4_SYN;
}}
min="0"
step="1"
type="number" />
|